ChemBioScreen
  • FR |

annuaire

ROBERT Thomas

Responsable Technique Plateforme KISSfMise à jour le 05/01/2022

equipe

Plateforme

Brevets / Publications / Communications

Publications 
2021
Robert T, Dock-Bregeon AC, Colas P. Functional characterization of CDK10 and Cyclin M truncated variants causing severe developmental disorders Human Mutation : Manuscript submitted - humu-2021-0054

Oyallon B, Brachet-Botineau M, Logé C, Robert T, Bach S, Ibrahim S, Raoul W, Croix C, Berthelot P, Guillon J, Pinaud N, Gouilleux F, Viaud-Massuard MC, Denevault-Sabourin C. New Quinoxaline Derivatives as Dual Pim-1/2 Kinase Inhibitors: Design, Synthesis and Biological Evaluation. Molecules. 2021 Feb 6;26(4):867. doi: 10.3390/molecules26040867. 

Princival I, Princival J, da Silva E, Lima S, Carregos J, de Lucenaa A, Halwass F, Franc J, Ferreir L, Hernandes M, Saraiv K, Peixoto K, Baratte B, Robert T, Bach S, Gomes D, Paiva D, Marchand P, Rodrigues M and da Silva T. Streptomyces hygroscopicus UFPEDA 3370: a valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells. Chemico-Biological Interactions.5 janvier 2021; 333: 109316. doi: 10.1016 / j.cbi.2020.109316

Bazin A, Cojean S, Pagniez F, Bernadat G, Cavé C, Ourliac-Garnier I, Nourrisson M-R, Morgado C, Picot C, Leclercq O, Baratte B, Robert T, Späth GF, Rachidi N, Bach S, Loiseau PM, Le Pape P and Marchand P. In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition. European Journal of Medicinal Chemistry. 15 janvier 2021; 210: 112956. doi: 10.1016 / j.ejmech.2020.112956

2020
Robert T, Johnson JL, Guichaoua R, Yaron TM, Bach S, Cantley LC, Colas P. Development of a CDK10/CycM in vitro Kinase Screening Assay and Identification of First Small-Molecule Inhibitors. Front. Chem., 27 February 2020 | https://doi.org/10.3389/fchem.2020.00147

Ibrahim N, Bonnet P, Brion JD, Peyrat JF, Bignon J, Levaique H, Josselin B, Robert T, Colas P, Bach S, Messaoudi S, Alami M, Hamze A. Identification of a new series of flavopiridol-like structures as kinase inhibitors with high cytotoxic potency. Eur J Med Chem. 199:112355. doi: 10.1016/j.ejmech.2020.112355.

Wilde M, Arzur D, Baratte B, Lefebvre D, Robert T, Roisnel T, Le Jossic-Corcos C, Bach S, Corcos L and Erb W. Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation. The article was first published on 10 Nov 2020. New J. Chem.10 Nov 2020, https://doi.org/10.1039/D0NJ05334A.