1.      Bazin MA., Cojean S., Pagniez F., Bernadat G., Cavé C., Ourliac-Garnier I., Nourrisson M.-R., Morgado C., Picot C., Leclercq O., Baratte B., Robert T., Späth G.F., Rachidi N., Bach S., Loiseau P.M., Le Pape P., Marchand P. 2021. In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition. Eur J Med Chem. Jan 15;210:112956. doi: 10.1016/j.ejmech.2020.112956. Epub 2020 Oct 23. PMID: 33148491

2.      Garcia-Princival IMR, Princival JL, Dias da Silva E, de Arruda Lima SM, Carregosa JC, Wisniewski A Jr, de Lucena CCO, Halwass F, Alves Franca JA, Ferreira LFGR, Hernandes MZ, Saraiva KLA, Peixoto CA, Baratte B, Robert T, Bach S, Gomes DC, Guedes Paiva PM, Marchand P, Rodrigues MDD, Gonçalves da Silva T. Streptomyces hygroscopicus UFPEDA 3370: A valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells. Chem Biol Interact. 2021 Jan 5;333:109316. doi: 10.1016/j.cbi.2020.109316. Epub 2020 Dec 4. PMID: 33285127

3.      Juillet C, Ermolenko L, Boyarskaya D, Baratte B, Josselin B, Nedev H, Bach S, Iorga BI, Bignon J, Ruchaud S, Al-Mourabit A. From Synthetic Simplified Marine Metabolite Analogues to New Selective Allosteric Inhibitor of Aurora B Kinase. J Med Chem. 2021 Jan 28;64(2):1197-1219. doi: 10.1021/acs.jmedchem.0c02064. Epub 2021 Jan 8. PMID: 33417773

4.      Brahmaiah D, Kanaka Durga Bhavani A, Aparna P, Sampath Kumar N, Solhi H, Le Guevel R, Baratte B, Ruchaud S, Bach S, Singh Jadav S, Raji Reddy C, Roisnel T, Mosset P, Levoin N, Grée R. Discovery of DB18, a potent inhibitor of CLK kinases with a high selectivity against DYRK1A kinase. Bioorg Med Chem. 2021 Feb 1;31:115962. doi: 10.1016/j.bmc.2020.115962. Epub 2020 Dec 31. PMID: 33422908

5.      Malikotsi A. Qhobosheane, Richard M. Beteck, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach, Lesetja J. Legoabe. Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors. Chemico-Biological Interactions, 343 (2021) ; https://doi.org/10.1016/j.cbi.2021.109478. 

6.      NG AMOUSSOU, R Osseni, A Laleye, B. Baratte, S. Ruchaud, S. Bach, JM Robert, A Bigot. Phytochemistry, toxicity and biological effects of fractions purified from Combretum paniculatum ethanolic extracts. JNat Product. 2020. Soumis.

7.      Ahmadu AA, Delehouzé C, Haruna A, Mustapha L, Lawal BA, Udobre A, Baratte B, Triscornia C, Autret A, Robert T, Bulinski JC, Rousselot M, Simoes Eugénio M, Dimanche-Boitrel MT, Petzer JP, Legoabe LJ, Bach S. Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor. Molecules. 2021 Jul 29;26(15):4599.

8.      Qhobosheane MA, Beteck RM, Baratte B, Robert T, Ruchaud S, Bach S, Legoabe LJ. Exploration of 7-azaindole-coumaranone hybrids and their analogues as protein kinase inhibitors. Chem Biol Interact. 2021 Jul 1;343:109478.

9.      Pieterse L., Beteck R.M., Baratte B., Jesumorotia O., Robert T., Ruchaud S., Bach S., Legoabe L. J. Synthesis and biological evaluation of selected 7H-pyrrolo[2,3-d]pyrimidine derivatives as novel CDK9/CyclinT and Haspin inhibitors. Chemico-Biological Interactions. 2021. https://doi.org/10.1016/j.cbi.2021.109643.

10.   Viet Hung Dao, Isabelle Ourliac-Garnier, Cédric Logé, Florence O. McCarthy, Stéphane Bach, Teresinha Gonçalves da Silva, Caroline Denevault-Sabourin, Jérôme Thiéfaine, Blandine Baratte, Thomas Robert, Fabrice Gouilleux, Marie Brachet-Botineau, Marc-Antoine Bazin, and Pascal Marchand. Dibenzofuran Derivatives Inspired from Cercosporamideas Dual Inhibitors of Pim and CLK1 Kinases. Molecules. 2021, Oct. 26(21), 6572. https://doi.org/10.3390/molecules26216572.

1.      Benchekroun M., Ermolenko L., Tran M.Q.,Vagneux A., Nedev H., Delehouzé C., Souab M., Baratte B., Josselin B., Iorga B., Ruchaud S., Bach S.* and Al-Mourabit A.* 2020. Discovery of simplified benzazole fragments derived from the marine benzosceptrin B as necroptosis inhibitors involving the receptor interacting protein kinase-1. Eur J Med Chem. Sep 1;201:112337. doi: 10.1016/j.ejmech.2020.112337. Epub 2020 Jun 25. PMID: 32659605

2.      Esvan Y., Josselin B., Baratte B., Bach S., Ruchaud S., Anizon F., Giraud F. and Moreau P. 2020. Synthesis and kinase inhibitory potencies of new pyrido[3,4-g]quinazolines substituted at the 8-position. Arkivoc. In press.

3.      Tuescher J. M., Tailfeathers D., Kernéis S.M., Baratte B., Ruchaud S., Bach S., Pouny I., Sautel F., and Golsteyn R.M. 2020. The Canadian prairie plant Thermopsis rhombifolia contains luteolin, a flavone that inhibits Cyclin dependent kinase 9 and arrest cells in the G1-phase of the cell cycle. The Journal of Natural Health Product Research. In press.

4.      Elie J, Feizbakhsh O, Desban N, Josselin B, Baratte B, Bescond A, Duez J, Fant X, Bach S, Marie D, Place M, Ben Salah S, Chartier A, Berteina-Raboin S, Chaikuad A, Knapp S, Carles F, Bonnet P, Buron F, Routier S, Ruchaud S.Design of new disubstituted imidazo[1,2-b]pyridazine derivatives as selective Haspin inhibitors. Synthesis, binding mode and anticancer biological evaluation. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1840-1853. doi: 10.1080/14756366.2020.1825408. PMID: 33040634

5.      Wilde M., Arzur D., Baratte B., Lefebvre D., Robert T., Roisnel T., Le Jossic-Corcos C., Bach S.*, Corcos L.* and  Erb W.* 2020. Regorafenib analogues and their ferrocenic counterparts: synthesis and biological evaluation. The article was first published on 10 Nov 2020. New J. Chem., https://doi.org/10.1039/D0NJ05334A.

6.      Mokhtari Brikci-Nigassa N, Nauton L, Moreau P, Mongin O, Duval RE, Picot L, Thiéry V, Souab M, Baratte B, Ruchaud S, Bach S, Le Guevel R, Bentabed-Ababsa G, Erb W, Roisnel T, Dorcet V, Mongin F. Functionalization of 9-thioxanthone at the 1-position : From arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest. Bioorg Chem. 2020 Jan;94:103347. doi: 10.1016/j.bioorg.2019.103347. Epub 2019 Oct 10. PMID: 31810757.

1.      Tazarki H, Zeinyeh W, Esvan YJ, Knapp S, Chatterjee D, Schröder M, Joerger AC, Khiari J, Josselin B, Baratte B, Bach S, Ruchaud S, Anizon F, Giraud F, Moreau P. New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis. Eur J Med Chem. 2019 Mar 15;166:304-317. doi: 10.1016/j.ejmech.2019.01.052.

2.      Motuhi SE, Feizbakhsh O, Foll-Josselin B, Baratte B, Delehouzé C, Cousseau A, Fant X, Bulinski JC, Payri CE, Ruchaud S, Mehiri M, Bach S. Neurymenolide A, a Novel Mitotic Spindle Poison from the New Caledonian Rhodophyta Phacelocarpus neurymenioides. Mar Drugs. 2019 Feb 1;17(2). pii: E93. doi: 10.3390/md17020093.

3.      Zeinyeh W, Esvan YJ, Josselin B, Baratte B, Bach S, Nauton L, Théry V, Ruchaud S, Anizon F, Giraud F, Moreau P. Kinase inhibitions in pyrido[4,3-h] and [3,4-g]quinazolines: Synthesis, SAR and molecular modeling studies. Bioorg Med Chem. 2019 May 15;27(10):2083-2089. ISSN 0968-0896. doi: 10.1016/j.bmc.2019.04.005. Epub 2019 Apr 4. 

4.      Ziane S., Mazari M.M., Safer A.M., Sad El Hachemi Amar A., Ruchaud S., Baratte B. and Bach S. 2019. Comparison between Conventional and Nonconventional Methods for the Synthesis of Some 2-Oxazolidinone Derivatives and Preliminary Investigation of Their Inhibitory Activity Against Certain Protein Kinases. Russian Journal of Organic Chemistry. July 2019, Volume 55, Issue 7 (1061–1069). doi.org/10.1134/S1070428019070248.

5.      Nguyen TN., Feizbakhsh O., Sfecci E., Baratte B., Delehouzé C., Garcia A., Moulin C., Colas P., Ruchaud S.*, Mehiri M.*, and Bach S. * 2019. Kinase-Based Screening of Marine Natural Extracts Leads to the Identification of a Cytotoxic High Molecular Weight Metabolite from the Mediterranean Sponge Crambe tailliezi. Mar Drugs. 2019 Oct 9;17(10). pii: E569. doi: 10.3390/md17100569.

6.      Anne Cecília Nascimento da Cruz, Dalci José Brondani, Temístocles I´talo de Santana, Lucas Oliveira da Silva, Elizabeth Fernanda da Oliveira Borba, Antônio Rodolfo de Faria, Julianna Ferreira Cavalcanti de Albuquerque, Sylvie Piessard, Rafael Matos Ximenes, Blandine Baratte, Stéphane Bach, Sandrine Ruchaud, Francisco Jaime Bezerra Mendonça Junior, Marc-Antoine Bazin, Marcelo Montenegro Rabello, Marcelo Zaldini Hernandes, Pascal Marchand *, Teresinha Gonçalves da Silva * Biological Evaluation of Arylsemicarbazone Derivatives as Potential Anticancer Agents. Pharmaceuticals 2019, 12, 169; doi:10.3390/ph12040169

7.      Frédéric Lassagne,* Camille Duguépéroux, Carlos Roca, Concepcion Perez, Ana Martinez, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach,* William Erb, Thierry Roisnel and Florence Mongin*. From simple quinoxalinesto potent oxazolo[5,4-f]quinoxaline inhibitors of glycogen-synthase kinase 3 (GSK3). Organic & Biomolecular Chemistry, 2019, DOI:10.1039/C9OB02002K